BM-MSC (the cell product) were prepared and infused into the damaged articulation(s) of each patient (60 × 10 6 cells in 3 weekly/doses). A cohort of 10 patients with functional and radiological evidences of hip osteoarthritis, either in one or both legs, was included in the study. The above rationale is sustained by the notion that MSCs express a chondrocyte differential potential and produce extracellular matrix molecules as well as regulatory signals, that may well contribute to cure the function of the damaged hip joint. To learn more about stem cell therapy for joint pain, book an appointment with Texas Orthopaedic Associates online or over the phone today.This study was performed to investigate the safety and efficacy of the intra-articular infusion of ex vivo expanded autologous bone marrow-derived mesenchymal stem cells (BM-MSC) to a cohort of patients with articular cartilage defects in the hip.
#Stem cell treatment for hips series
Before recommending any treatment, your provider will perform a series of evaluations to ensure stem cell therapy is the best choice for you.Ĭhronic joint pain tends to worsen over time, and the sooner you have treatment, the faster you’ll find relief. Stem cell therapy can be a great choice for many patients, but it’s not the only joint treatment our practice offers. Find out if stem cell therapy is right for you Those improvements may continue for several months as cartilage repair takes effect. It takes awhile for stem cells to transform or “differentiate” into new cells, and most patients begin to experience benefits of their therapy within about six weeks. The therapy is performed on an outpatient basis, and our team will give you care instructions, including activity restrictions, to give the area time to heal. The harvested cells are prepared and purified to remove debris.Then, the cells are injected into the area of cartilage damage. Typically, our team harvests cells from bone marrow in your hip or pelvis using a long, special needle and local anesthetic to keep you comfortable. Stem cell therapy starts with a simple procedure to harvest the stem cells from your body. Today, doctors use mesenchymal stem cells that are extracted from your own fatty tissue or bone marrow. In the very early days of stem cell therapy, researchers used embryonic stem cells, resulting in a lot of controversy over the treatments. When stem cells are implanted at the site of cartilage damage, those stem cells may become new cartilage cells that can replace cartilage cells that have been damaged. The “transformation” happens when the stem cells are acted on by other cells and chemical “triggers.” Stem cells are like the “blank slates” of your body, able to transform into many different kinds of cells, including cartilage, muscle, and bone cells. Until the advent of stem cell therapy and regenerative medicine, joint replacement surgery was the only way to “cure” symptoms caused by damaged cartilage. Medication and physical therapy may help lessen symptoms, but these treatments won’t repair damaged cartilage.
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As the cartilage layer wears away, pain, stiffness, and other symptoms grow worse, sometimes leading to permanent disability. People whose jobs require lots of squatting or liftingĬartilage damage eventually leads to arthritis and inflammation, which in turn causes more cartilage damage.Some people are more prone to cartilage damage, including: But most cartilage damage happens from years of wear and tear on the joint surfaces. As an integral part of your joints, cartilage protects your bones from damage when you bend and flex your joints, and it also helps your joints move smoothly and without pain.Ĭartilage can be damaged from traumatic injuries, like falls or sports injuries. Cartilage 101Ĭartilage is a thick, slick, rubbery material that covers the surfaces of bones in your joints. If you have aching joints, here’s how stem cell therapy could help. In fact, cartilage damage is an integral part of arthritis, a condition affecting about a quarter of American adults.Īs a leading orthopaedics practice with offices in Dallas, Plano, Keller, Weatherford, and Fort Worth, Texas, Texas Orthopaedic Associates treats cartilage damage with state-of-the-art stem cell therapy aimed at repairing damaged cartilage without surgery.
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Cartilage damage is common, especially in weight-bearing joints like the knees and hips or the large ball-and-socket shoulder joints.